Structural Modification of the P2' Position of 2,7-Dialkyl-Substituted 5(S)-Amino-4(S)-hydroxy-8-phenyl-octanecarboxamides: The Discovery of Aliskiren, a Potent Nonpeptide Human Renin Inhibitor Active after Once Daily Dosing in Marmosets
Total Synthesis of “Aliskiren”: The First Renin Inhibitor in Clinical Practice for Hypertension
EP2075244A1 - New route to building block for making renin inhibitors - Google Patents
Aliskiren: the first renin inhibitor for clinical treatment
Aliskiren fumarate, CGP-60536(free base), SPP-100B, SPP-100(free base), CGP-60536B-药物合成数据库
Convergent Synthesis of the Renin Inhibitor Aliskiren Based on C5–C6 Disconnection and CO2H–NH2 Equivalence
Convergent Synthesis of the Renin Inhibitor Aliskiren Based on C5–C6 Disconnection and CO2H–NH2 Equivalence
Aliskiren: the first renin inhibitor for clinical treatment
ALISKIREN – All About Drugs
Luca BANFI, Università degli Studi di Genova, Genoa, UNIGE, Department of Chemistry and Industrial Chemistry
ALISKIREN – All About Drugs